Gonorrhea, the second most notifiable disease in the US, is rapidly becoming resistant to Fluoroquinolones, such as Cipro according to the CDC. Physicians are advised to use the last line of defense, the Cephalosporins. In the April 13th issue of the Morbidity and Mortality weekly, the Center for Disease Control reported there was 13% overall resistance. In some areas 39% of the bug is resistant to the Fluoloquinolones. On the basis of this evidence the CDC
"No longer recommends the use of Fluoroquinolones for the treatment of gonococcal infections and associated conditions such as pelvic inflammatory disease."
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